fungi and its activity , in decelorization


ABSTRACT
With the successful increase in the textile industry it also produces some drawback by which human population has to go through. Although textile produces colorful clothes for us but it also produces the waste effluent of dyes. The textile industries produce effluents that contain several types of chemicals such as dispersants, leveling agents, acids, alkalis, carriers and various dyes. Accumulation of concentrated sludge from natural dyes creates a disposal problem. Brown Rot Fungi (BRF) are the most harmful microorganisms in wood decay process. BRF, causes wood decay primarily by attacking the carbohydrates of the cell walls, leaving lignin essentially undigested. BRF are extensively used in industry and are best option for enzyme production, biodegradation and decolorization of dyes from wastewater of textile effluent. Despite their loss of enzymatic systems, the BRF are still capable of depolymerizing holocellulose and extensively modifying lignin. In this study the BRF samples would be collected and will isolate BRF. Identify it on the morphological basis. BRF will culture on Malt Extract Agar to isolate its enzymes.  Assay of decolorization will be done for selected species of BRF against selected Synthetic and natural dyes. The outcome of the study will contributes to purify and characterize the important enzymes, and to evaluate its applicability for the decolorization of synthetic and natural dyes. The aim of this study to remove dyes from large volumes of effluents at very low in cost and will help to secure the environment from harmful textile waste water effluent.


INTRODUCTION
Attraction of human beings towards colors is a natural property and every person has his own choice and liking for color. The icy appearance of Hamaliyan ranges or lush green forests or fields of agriculture or trees laden with colorful fruits or butterflies moving from flower to flower show the beauty of nature, generation after generations are being attracted. Color is visual property of humans categorizing as green, black, blue etc. (Mizzarini et al., 2002).
Colorants can be pigment or a dye which has the ability to absorb or emit the radiations in the visible range of 400-700nm. Based on the structure and mechanisms of production they can be organic or inorganic. A compound gives color due to the absorption of certain electromagnetic radiation from the visible region (Younas, 2006). Dyes can absorb radiations of different wavelength in the visible range of spectrum. Human eyes detect the visible radiations only for the respective complementary colors (Vankar,  2005).
Dye is any natural or synthetic substance which is used to color different materials. In fact dye is a colored substance that has the ability to bind with material to which it is applied. There are two types of dyes
1. Natural dyes
2. Synthetic dyes.
Synthetic dyes are highly coloured organic substances that bind with fiber with the aid of chemical forces. Hence synthetic dye gives variety of reproducible shades and colors, had replaced natural dye in textiles (Deo and Desai, 1999).
Dyes are synthesized in many ways by using different chemicals. On the basis of methods of application dyes are classified as, acid dyes are anionic in nature and make ionic bond with fiber when dissolved in acidic solution. Mostly these dyes are used for wool, acrylic, nylon and cotton. Because these dyes are used on fibers in inorganic or organic acid solutions that’s why known as acidic dyes. Azoic dyes used to dye Cotton. These dyes have azo component (–N=N-). This type of dye is particularly fast to light. Basic dyes are cationic in nature and also make ionic bond with acrylic, polyester and nylon. These are made up of amino acids and mostly used on paper. (Gurr, 2012). 
Direct dyes are also azo dyes applied generally on cotton-silk combination from neutral or slightly alkaline baths containing additional electrolyte. (Diwaniyan et al., 2010). Sulfur dyes require careful processing because its reduce form is soluble in water whereas oxidized form is insoluble. These dyes are used for dyeing cotton and rayon. These dyes are fast to washing but poorly fast to chlorine and give dark and dull colors (Diwaniyan et al., 2010).
Dyes are synthesized in a reactor, filtered, dried, and blended with other additives to produce the final product. Following steps are mostly used for the synthesis of dye such as coupling, amination, sulfonation, halogenation, diazotization, and following separation methods used that are distillation, precipitation, and crystallization (Gurr, 2012). In general, organic compounds such as naphthalene are reacted with an acid or an alkali along with an intermediate (a nitrating or a sulfonation compound) and a solvent to form a dye mixture. (Mekkawy, et al., 1998).
The use of natural dye is not a new method, it is an ancient method. As early as 180000, the Neanderthal tribe prepared their dead bodies for burial by coating with red ochre also known as ferric oxide. After this success, they made paintings in cave by using yellow and red iron oxide, black manganese dioxide and white clay. For tens of thousands of years humans obtained coloring materials from salts, rocks, and earth tones (Singh et al., 2015).
The value of natural dye was lowered after the invention of first synthetic dye in 1856. The synthetic dye got popularity due to extensive use in different fields such as food cosmetics, nonlinear optical activity and in textile industries. But in last few decades value of synthetic dye is lowered due to its hazardous effect on both health and environment. The most common health problems of synthetic dyes are allergy and cancer and it is non biodegradable (Zarkogianni et al., 2011).
            Now a day’s pollution has become a challenge for chemical industries worldwide. Today, All over the world environment regulations are becoming stricter, So we should realize the importance of natural dye and its technology to prevent the pollution (Ekta  et al,. 2005).
Natural dyes may have a wide range of shades. The most of natural dyes are obtained from different part of plant such as roots, berries, bark, fruits, leaves, and wood and other biological sources such as Fungi and lichens are also used. Natural dyes are known for their use in coloring of food substrate, leather, and wood as well as natural fibers like wool, silk, cotton and flax as major areas of application since ancient times (Chengaiah et al., 2010). Many natural dye stuff and stains were obtained mainly from plants and dominated as sources of natural dyes producing different colors like red yellow, blue, black, brown, and a combination of these. Almost all part of the plants like root, leaf, wood, seed, flower, etc. produce dyes. It is interesting to note that over 2000 pigments are synthesized by various parts of plants (Siva, 2007).
These dyes are eco-friendly than synthetic dyes because in natural materials, all synthesis processes are accomplished by nature with no pollution of environment and these materials are readily biodegradable and do not produce hazardous chemicals on degradation in environment, and so, there is no need for further treatment of chemical before discharging into the environment (Newman et al., 2012). If you are going for a soft hue or soothing shade, natural dyes can help you achieve that look (Farizadeh et al., 2009).
Basidiomycota (basidiomycetes) make up 32% of the Fungi and include most wood decaying species, as well as pathogens and mutualistic symbionts. Wood-decaying basidiomycetes have typically been classified as either white rot or brown rot, based on the ability (in white rot only) to degrade lignin along with cellulose and hemicellulose. Prior genomic comparisons suggested that the two decay modes can be distinguished based on the presence or absence of ligninolytic class II peroxidases (PODs), as well as the abundance of enzymes acting directly on crystalline cellulose .(Riley et al., 2014)
BRF are the most prevalent with regard to attack on coniferous, structural wood products in North America. The wood decayed by BRF is typically brown and crumbly and it is degraded via both non-enzymatic and enzymatic systems. A series of celluloytic enzymes are employed in the degradation process by BRF, but no lignin degrading enzymes are typically involved (Goodell et a.l, 2008). These BRF are typically found at high elevations in pine forest regions, or in coniferous forest regions such as the Rocky Mountains or the Himalayas (Isaac, 1993).
The biological decomposition of lignocellulosic materials, in particular woody biomass by Wood Rotting Basidiomycetes, plays an essential role in carbon circle. It has long been proposed that brown-rot attack is based on a two-step process. Based on research with gloeophyllum species, have been suggested as the potential biodegrative mechanism in BRF. Despite their loss of enzymatic systems, the BRF are still capable of depolymerizing holocellulose and extensively modifying lignin. The Brown Rot Fungi have cast off the physiologically (energetically) expensive apparatus of lignocellulose degradation employed by White Rot Fungi, and they have in turn acquired alternative lower energy mechanisms to initiate fungal attack of wood to enhance the efficiency of their utilization of lignocellulse (Arantes et al., 2014).
Objective
Aims of this study are
      Isolation and screening of BRF
      Study of Enzyme Profile
      Decolorization of natural dyes and synthetic dyes
REVIEW OF LITERATURE
Indian are considered as the ancestors for the art of natural dyes. But the knowledge of natural dying techniques and extracting them from different sources has been diminished as there was no documentation for those techniques due to the following reason naturally dyes are difficult to be successful in commercial sector. With the changes in environment condition i.e pollution global warming environmentalist now again move toward the use of natural dyes. Due to the properties biodegradable non carcinogenic and no or less chemical usage (Arora, et al., 2017).
Different plants in combination or other natural source provides us the cost effective and average colour range is produced within a range of synthetic colorants (Geissler, 2009). Shoving on reducing chemical usage in extraction process, its recommended to explicit usage  of water solvent in procedure of dye extraction from different sources for example plans leaves and fruits (Shaid et al., 2013).
Highly contaminated waste water or may be plant residues when we use solvents in extraction process which requires after treatment putting an extra cost. Combined dye extraction and dying process simultaneously is suggested to reduce cost.low dye extraction rate increases the expense of dying and also the dye present in the waste water should be removed to legal limits of effluents (Mussak and Bechtold, 2009).
As natural dye producing source i.e. plants have low content of dyes they required high quantity of biomaterial and also the huge waste generation creates additional burden to dispose waste. Research findings on using enzyme as fabric pretreatment method offers a cost-effective and environmentally favorable soft chemistry option as enzymes are specific and fast in action and small amounts of enzyme often save large amounts of raw materials, chemicals, energy and water (Shaid et al., 2013). We can reuse the dye liquor in dying cycle repetition it would interesting (Vankar et al., 2007). If we reuse the waste water of natural dying process it would cost saveing as in case of madder reduces the 19.91 cost (Shams, 2012).
Sonication dye extraction and dying process is other way over the traditional thermal extraction method .i will increases the dye production as well as the lower the effluent load of natural dyes (Sivakumar et al., 2009). Natural dye leftover as heavy metal adsorbents could be useful in remediation of groundwater and surface water of chrome metals in contaminated sites of tannery operations.
In Pakistan work has been done on natural dyes. Study was conducted to explore the coloring potential of Harmala (Peganum harmala) seeds and to improve color strength of dye using microwave radiations followed by a mordanting process (Adeel et al., 2018).
Dyes derived from natural materials such as plant leaves, roots, bark, insect secretions, and minerals were the only dyes available to mankind for the coloring of textiles until the discovery of the first synthetic dye in 1856. Rapid research strides in synthetic chemistry supported by the industrialization of  textile production not only led to the development of synthetic alternatives to popular natural dyes but also to a number of synthetic dyes in various hues and colors that gradually pushed the natural dyes into oblivion (Verma, and Gupta, 2017).
Textile and dyeing industries use various synthetic dyes. Effluents, containing 5–10% of dyestuffs, are usually discharged into natural water bodies. Conventional biological systems are not efficient for bioremediation and decolorization of dyes (Yesilada et al., 2018).
Both synthetic and natural dyes are widely used in various industries particularly in Textile Industries. Many harmful and hazardous effects of synthetic dyes have been reported, but these are using very commonly worldwide. One of the most important problems of synthetic dyes is its decolorization. Scientists have been trying to remove the colour with the help of certain chemicals, Fungi, bacteria, algae, and many other techniques, but Biological Decolorization of Synthetic Dyes is very common and most effective method ( Joshi, et al., 2018).
Several methods have already been used to treat textile effluents including physico-chemical methods such as filtration, carbon activated, coagulation and chemical flocculation. Although these methods are effective, but they are expensive and involve formation of concentrated sludge that creates a secondary disposal problem. In recent years, use of bioremediation based technologies for treating textile wastewater containing dyes has attracted much interest. The ability of microorganisms and their dye degrading enzymes to decolorize and metabolize the dyes has long been known and has proved to be the best option for bioremediation (Singh et al., 2015). The biodegradation of synthetic dyes by Fungi is emerging as an effective and promising approach (Yang et al., 2016).
The fungal decolorization of dye wastewater has been performed in recent years. Several Fungi with the capability to decolorize a wide range of dyes have been reported. For example, the white-rot Fungi and BRF are well-studied Fungi groups with decolorization abilities (Singh and Singh 2014).
The mechanism of fungal decolorization mainly involves two aspects, biodegradation and biosorption (Vanhulle et al., 2007). The biodegradation capability of Fungi is due to their extracellular, non-specific and non-selective enzyme system (Baccar et al., 2011).
Fungal enzyme production depends on nutrient limitations, and their subsequent dye decolorization ability is achieved depending on the growth conditions (Kaushik, & Malik, 2009). Decolorization of different dyes by an indigenous strain of fungus from Eucalyptus tree. Their study has been proved that from number of different synthetic dyes (RBBR, Malachite Green, and Congo red) Mucor hiemalis decolorize RBBR dye most efficiently. Ideal conditions for decolorization of 50 ppm RBBR dye has been achieved at 30°C, 5.0 pH and shaking speed of 130 rpm for both free and immobilized biomass although complete decolorization has been achieved in more than one week. The investigations have been proved the higher decolarization capacity of immobilized biomass then free fungal biomass (Rai and Sati, 2015).
Fungi especially white rot Fungi and their enzymes (laccase, lignin peroxidase, and Mn peroxidase) can be used to bioremediate various xenobiotics and wastewaters. Therefore, white rot Fungi and/or their enzymes especially laccase may be an alternative biological system to bioremediate, decolorize, and detoxify textile dyes in water bodies originating from textile manufacturing facilities (Yesilada et al., 2018).
BRF selectively decay structural carbohydrates, with limited lignin degradation resulting in this component becoming elevated in brown-rotted wood. Changes in wood chemistry following brown-rot decay have been investigated. BRF break down hemicellulose and cellulose that form the wood structure. Cellulose is broken down by hydrogen peroxide (H2O2) that is produced during the breakdown of hemicellulose (Deacon, 2005). Because hydrogen peroxide is a small molecule, it can diffuse rapidly through the wood, leading to a decay that is not confined to the direct surroundings of the fungal hyphae. As a result of this type of decay, the wood shrinks, shows a brown discoloration, and cracks into roughly cubical pieces, a phenomenon termed cubical fracture. The Fungi of certain types remove cellulose compounds from wood and hence the wood becomes brown colour. Brown rot in a dry, crumbly condition is sometimes incorrectly referred to as dry rot in general. The term brown rot replaced the general use of the term dry rot, as wood must be damp to decay, although it may become dry later. Dry rot is a generic name for certain species of BRF (Monrroy et al., 2011).
BRF of particular economic importance include Serpula lacrymans (true dry rot), Fibroporia vaillantii (mine fungus), and Coniophora puteana (cellar fungus), which may attack timber in buildings. Other BRF include the sulfur shelfPhaeolus schweinitzii, and Fomitopsis pinicola (Stamets, 2005).
Brown-rot fungal decay is characterised by extensive demethylation of lignins whereas white-rot tends to produce low yields of molecules with demethylated functional groups (Vane et al., 2001).
We will collect Fungi from and isolate the BRF. Water Agar medium (WA; WA1.5% agar) shall use for the fungal isolation; potato-carrot-Agar medium (PCA; 5% potato, 5% carrot, 2% agar) would use for the identification of fungal isolates; potato-dextrose-Agar medium (PDA; 20% potato, 2% dextrose, 2% agar) will use to grow the fungal cultures and for the DNA extraction; and Malt Agar medium (MEA; 2% malt extract, 1.5% agar) will use for screening the decolorization by Fungi. The liquid MEA medium will use for the decolorization test was the same as that described above but without agar. The PDA medium would use for colony growth, and the genomic DNA isolation shall prepare following the Wongsawas method.
Dye decolorization on solid media would done by the solid media that will prepare with MEA medium and the addition of each dye to a total concentration of 50 mg/L. A mycelium plug derived from the edge of fungal strains grown on WA medium plates for 4 days at 25 °C will transfer to the center of a solid medium plate and will inoculate at 25 °C for 1 week. The formation of decolorized zones under or around the developing mycelia will monitore for dye decolorization.
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